Heterociklična jedinjenja su ciklična jedinjenja koja pored ugljenika sadrže u strukturi prstena jedan ili više atoma nekih drugih elemenata-. Start studying Heterociklična jedinjenja (Petočlana). Learn vocabulary, terms, and more with flashcards, games, and other study tools. izvor: Wikipedia. Stranice: Poglavlja: Heterociklična Jedinjenja (2 prstena), Heterociklična Jedinjenja (3 prstena), Heterociklična Jedinjenja (4 ili više.

Author: Vigal Tygojin
Country: Mongolia
Language: English (Spanish)
Genre: Automotive
Published (Last): 2 February 2011
Pages: 225
PDF File Size: 12.27 Mb
ePub File Size: 11.96 Mb
ISBN: 959-6-23673-903-9
Downloads: 81788
Price: Free* [*Free Regsitration Required]
Uploader: Goltikazahn

Oh no, there’s been an error

Almqvist, Microwave-assisted synthesis and functionalization of 2-pyridones, 2-quinolones and other ring-fused 2-pyridones, Top. Therefore, it is essential, if the reaction is carried out in a closed reactor, to maintain the volume and concentration of reactants low, in order to shift the equilibrium towards the products. The review is divided in three parts. Valentic, Synthesis and investigation of solvent effects on the ultraviolet jeedinjenja spectra of 5-substitutedmethylcyanohydroxypyridones, J.

TFA was used as a proton source reducing the formation of byproducts and increasing the isolated yields. Twieg, The forgotten liquid crystals of Daniel Vorlander: This issue requires jedibjenja attention and is beyond the scope of this paper.

Agarwal, Microwave prompted multigram synthesis, structural determination, and photo-antiproliferative activity of fluorinated 4-hydroxyquinolinones, Bioorg.

Heterociklično jedinjenje — Википедија, слободна енциклопедија

Brkovic and Aleksandar D. This synthesis is given in Figure 2. A case study, Tetrahedron 58 Health, A 46 Mijin, A Kinetic study of Beterociklicna rugosa lipase-catalyzed synthesis of 4,6-dimethylcyanopyridone, J. For example, the modern pharmaceutical industry requires the creation of a growing number of new molecules, forcing chemists to ejdinjenja a number of experiments in a short period of time [45]. This method cannot be applied in cases where an electron-acceptor group e.

Similarly, the synthesis of heterociklina 5-phenylazohydroxymethylcyanopyridones starting from [beta]-phenylazo ketoesters under the same conditions was performed Figure 7, Table 1, entries Dihydrooxazolo and dihydrothiazolo ring fused 2-pyridones were prepared using microwave assisted organic synthesis in good yields and high enantiomeric purity.


First, we will discuss the microwave synthesis of 2-pyridones. The short reaction time and the increasing number heterociklicnaa microwave assisted reactions lead to the application of this technique in the various fields of industry.

It was demonstrated that the sulfur in the pilicide scaffold could be exchanged for oxygen with an almost retained pilicide activity.

Heterociklično jedinjenje

Strauss, The use of palladium on porous glass for catalytic coupling reactions, Chem. Different combinations of fragments were used: Dyachenko, Synthesis and properties of 3-cyanopyridine-2 1H -chalcogenones. Konvencionalni nacin izvodenja organskih sinteza podrazumeva zagrevanje spoljasnjim izvorima toplote pri cemu se toplota prenosi kondukcijom, jedinjenna predstavlja spor i neefikasan metod prenosa energije, jer zavisi od toplotne provodljivosti materijala, pa je temperatura reaktora veca od temperature reakcione smese.

Zhu, One-pot synthesis of pyridones and related compounds under microwave irradiation in water, Jiamusi Hetsrociklicna Xuebao Ziran Kexueban 28 Visser, Rapid microwave-enhanced synthesis of 4-hydroxyquinolinones under solvent-free conditions, Tetrahedron Lett.

Wang, Microwave-assisted solvent-free synthesis of substituted 2-quinolones, Tetrahedron 63 Mijin, Synthesis of 5- substituted phenylazo hydroxymethylcyanopyridones from ethyl 3-oxo substituted phenylazo butanoates, J.

Kategorija:Heterociklična jedinjenja kiseonika – Wikiwand

Shen, The 2-pyridone antibacterial agents: Sasi, Microwave-assisted synthesis of quinoline alkaloids: US US Kappe, Controlled microwave heating in modern organic synthesis, Angew. It should be noted that 4-pyridone, isomer of 2-pyridone, due to mesogenic properties, is used in the synthesis of liquid crystals [19]. Among them, 2-pyridone compounds are particularly significant Figure 1. Microwave synthesis was performed using a conventional microwave oven in the absence of solvent.

Available online at the Journal website: Microwave technology is used in both synthetic steps. Shi, New potential calcium channel heterociklicma In this paper, the synthesis of 2-pyridones as well as 2-pyridone-based compounds, such as 2-quinolones, using microwave assisted organic chemistry is reviewed.

In this synthesis, product was obtained starting from cyanoacetamide, ethyl cyanoacetate and ethylamine. Reactions were performed in 1,2-dichloroethane DCE at [degrees]C for s [80].


Mohan, Bismuth Compounds in Organic Synthesis.

Due to increased product yields and purity, lower waste and sometimes solvent free conditions, microwave assisted syntheses are among the methods that respect the principles of the “green chemistry”. Synthesis can be also performed in the solid phase.

Most of these compounds possess antibacterial [2,3], antifungal [4], anti-inflammatory [5], antiviral [6,7], antitumor [8] and antiplatelet [9,10] properties. Aromatic heterocyclic compounds represent an important group of compounds due to their biological and medical applications. Shi, An efficient and greener approach to the synthesis of 3,5-dicyanopyridin-2 1H -one derivatives in aqueous media under microwave irradiation conditions, J.

Mijin, Influence of process parameters on the photodegradation of synthesized azo pyridone dye in Ti[O. Nasuprot tome, mikrotalasno zracenje je efikasan izvor zagrevanja koji direktno prenosi energiju kroz interakciju sa polarnim molekulima prisutnim u reakcionoj smesi. Microwave synthesis is among methods that respect the principles of the so-called “green chemistry” which is one more reason for performing this type of synthesis [50].

Preparation of 3-arylpyridone analogues generated by solution- and solid-phase parallel synthesis methods, Bioorg. The synthesized derivatives of 4,6-dimethylcyanopyridone Table 1, entries were obtained in nearly quantitative yield, while the derivatives of 4,6-diphenylcyanopyridones Table 1, entries were obtained in lower yields.

Synthesis of other ring fused 2-pyridone derivatives In the last part of this review, the synthesis of condensed derivatives of 2-pyridone ring fused N-substituted 2-pyridones will be presented. Abdou, Microwave-assisted synthesis of 2 1H -pyridones and their glucosides as cell proliferation inhibitors, Nucleos.